In DSM-III, this disorder is called Intoxication

Diagnostic Criteria

A. Development of a substance-specific syndrome that follows the recent ingestion and presence in the body of a substance.

B. Maladaptive behavior during the waking state due to the effect of the substance on the central nervous system, e.g., impaired judgment, belligerence.

C. The clinical picture does not correspond to any of the specific Organic Brain Syndromes, such as Delirium, Organic Delusional Syndrome, Organic Hallucinosis, or Organic Affective Syndrome.

Differential Diagnosis

Other Organic Mental Disorders

When the criteria for Delirium, Organic Hallucinosis, Organic Delusional Syndrome or Organic Affective Syndrome are met following the ingestion of a substance, these conditions are diagnosed, because Intoxication is a residual category.

Neurological diseases

Many neurological diseases can produce symptoms, such as slurred speech and incoordination, that resemble an Intoxication.


Diagnostic Criteria

A. The development of a reversible substance-specific syndrome due to recent ingestion of (or exposure to) a substance. Note: Different substances may produce similar or identical syndromes.

B. Clinically significant maladaptive behavioral or psychological changes that are due to the effect of the substance on the central nervous system (e.g., belligerance, mood lability, cognitive impairment, impaired judgement, impaired social or occupational functioning) and develop during or shortly after use of the substance.

C. The symptoms are not due to a general medical condition and are not better accounted for by another mental disorder.


See Substance-Related Disorders

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